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Visual abstract | Tacrolimus versus IV cyclophosphamide in patients with lupus nephritis

Sep 16, 2022
Learning objective: After reading this article, learners will be able to cite a new development in lupus nephritis.

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Lupus nephritis (LN) is a common issue that patients with systemic lupus erythematosus (SLE) develop, with up to 60% of patients developing this sequela.1 For patients with SLE, LN development is associated with a significant level of morbidity and mortality; therefore, there is an urgent need to identify treatment combinations that combat this.1

A recent publication by Zheng et al.1 in Rheumatology investigated the effect of tacrolimus against intravenous cyclophosphamide in Chinese patients with LN. The Lupus Hub is happy to provide a visual abstract summarizing the data from this study.

Visual Abstract

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  1. Zheng Z, Zhang H, Peng X, et al. Effect of tacrolimus vs intravenous cyclophosphamide on complete or partial response in patients with lupus nephritis: A randomized clinical trial. 2022;5(3):e224492. DOI: 10.1001/jamanetworkopen.2022.4492


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