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Lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE), can have a significant impact on the morbidity and mortality of patients with SLE. Late diagnosis and insufficient disease control can result in chronic kidney disease, which can lead to kidney failure. Additionally, LN can result in adverse fertility and pregnancy outcomes, as well as cardiovascular morbidity and mortality in later life. Early diagnosis, rapid and effective treatments, and a sustained immunologic response are vital for improved outcomes for patients with LN.