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Patients with systemic lupus erythematosus (SLE) commonly experience immunosuppression, either as a result of the original disease or treatment for SLE; often leading to an increased risk of infections. In the general population, vaccinations are commonplace as prophylactic measures for infection. However, concerns over a possible link between the development or exacerbation of SLE following vaccination has led to uncertainty over administering vaccines in patients with SLE.
Here, we summarize a meta-analysis by Wang et al.1 published in Arthritis Research & Therapy on the association and risk for the development of SLE following vaccination.
Figure 1. Odds ratio for SLE by history of vaccination*
CI, confidence interval; HBV, hepatitis B; HPV, human papillomavirus.
*Data from Wang, et al.1
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