What are some of the key updates in the management of lupus during pregnancy?

During the 14th European Lupus Meeting 2024, the Lupus Hub was pleased to speak with Jill Buyon, New York University, New York, US. We asked, What are some of the key updates in the management of lupus during pregnancy?

Firstly, Jill Buyon discusses two ongoing studies investigating pregnancy outcomes in women with anti-Ro antibodies or antiphospholipid antibodies. The first study, Surveillance and Treatment tO Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ, NCT04474223), focuses on monitoring maternal anti-Ro antibodies and using fetal heart rate monitoring to detect advanced disease, thereby offering possibilities for early intervention and improved monitoring strategies. The second study, IMProve Pregnancy in APS With Certolizumab Therapy (IMPACT, NCT03152058), aims to evaluate the efficacy of certolizumab in pregnant women with antiphospholipid syndrome.