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Patients with systemic lupus erythematosus (SLE) experience susceptibility to thrombotic events due to chronic inflammation, vascular damage, and acquired coagulation disorders resulting from antiphospholipid antibodies (aPL).
Nossent et al. recently published an article in Lupus, comparing the incidence rates (IRs), risk factors, and outcomes of a first venous thromboembolic event (VTE) between patients with SLE and controls. Here, we summarize their key findings.
Figure 1. Incidence rates per 1,000 person-years for VTE, PE, and VT in patients with SLE vs controls*
PE, pulmonary embolism; VT, venous thrombosis; VTE, venous thromboembolic event, SLE, systemic lupus erythematosus
*Data from Nossent , et al.1
Figure 2. Adjusted hazard ratio for association between A risk factors and a first VTE and B death and arterial events following first VTE in patients with SLE vs controls*
aHR, adjusted hazard ratio; CI, confidence interval; SLE, systemic lupus erythematosus.
*Data from Nossent, et al.1
Key learnings |
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