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2022-10-11T15:18:37.000Z

Visual abstract | The TULIP trials: Post hoc analysis of sustained glucocorticoid tapering with anifrolumab management of SLE

Oct 11, 2022
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Learning objective: After reading this article, learners will be able to cite a new development in systemic lupus erythematosus.

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The Lupus Hub is happy to present a visual abstract representing data from a post hoc analysis of the phase III TULIP-1 and TULIP-2 trials (NCT02446912 and NCT02446899), which evaluated the use of anifrolumab to support sustained glucocorticoid tapering in patients with systemic lupus erythematosus.1 Glucocorticoids remain the standard of care in ~80% of patients, but prolonged use is associated with toxicity and adverse events. Tapering glucocorticoid use in patients with SLE patients can lead to an improvement in patient-reported outcomes.1


 

Visual Abstract

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  1. Bruce IN, van Vollenhoven RF, Morand EF, et al. Sustained glucocorticoid tapering in the phase 3 trials of anifrolumab: a post-hoc analysis of the TULIP-1 and TULIP-2 trials. Rheumatology (Oxford). Online ahead of print. DOI: 10.1093/rheumatology/keac491

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